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2184 0. Appl. DE BROE4 and Driss ZAID3 1 Dr Salma Suleiman Dialysis Kidney Transplant Centre, Khartoum, Sudan 2 Universitary Hospital Habib Bourguiba, Sfax, Tunisia 3Universitary Hospital Ibn Rochd, Cassablanca, Morocco 4University of Antwerp, Belgium Introduction ___________________________________________________________611 Paraphenylene diamine (PPD) characteristics ______________________________612 Pharmaco-toxicology ___________________________________________________612 Clinical presentation ____________________________________________________613 Epidemiology 613 Clinical features and systemic toxicity 614 Nephrotoxicity 614 Other systems involvement 614 Treatment _____________________________________________________________616 References _____________________________________________________________ 617 Introduction Since 1883, paraphenylene diamine (PPD) has tra- ditionally been used for dyeing (dark color) hair in Europe [1- 2] as a fresh preparation mixed with hydro- gen peroxide (H2O2) .
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